Details
| Name | TMEM106B |
| Type | TF |
| Species | Homo sapiens |
| Tissue | neure |
| Experiment Method | NA |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | In summary, we identified a protective variant in the TMEM106B gene that may have a neuronal protection effect against general aging, independent of disease status, which could help elucidate the relationship between aging and neuronal survival in the presence or absence of neurodegenerative disorders. |
| Regulation Gene | TMEM106B |
| Year | 2020 |
| Pubmed ID | 31456032 |
| Title | The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion. |
| Drug | NA |
| Disease | AD |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | null |