Details
| Name | PPARGC1A |
| Type | TF |
| Species | Homo sapiens |
| Tissue | VSMC |
| Experiment Method | NA |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | Thus, PPARGC1A upregulates autophagy reducing senescence by a SQSTM1-dependent mechanism. We propose SQSTM1 as a novel target in therapeutic interventions reducing senescence. |
| Regulation Gene | PPARGC1A |
| Year | 2020 |
| Pubmed ID | 31441382 |
| Title | SQSTM1/p62 and PPARGC1A/PGC-1alpha at the interface of autophagy and vascular senescence. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | null |