A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name CASP
Type TF
Species Rat
Tissue kidneys,
Experiment Method NA
Up/Down Down
Pro/Anti Anti
Funtion Description these Casp3 KO kidneys showed proliferative glomerular lesions characterized by increased cells, matrices, immune complex depositions containing IgA and complement 3 in the mesangial area , podocyte injuries and inflammatory cell infiltrations in the tubulointerstitium.
Regulation Gene CASP
Year 2020
Pubmed ID 31440817
Title Immune-associated renal disease found in caspase 3-deficient mice.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput null