A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name GCN2
Type gene
Species Yeast
Tissue NA
Experiment Method RNA-Seq
Up/Down Down
Pro/Anti Anti
Funtion Description tRNA overexpression activated Gcn2 in young cells and extended lifespan in a manner dependent on Gcn4.
Regulation Gene NA
Year 2018
Pubmed ID 30117416
Title Ssd1 and Gcn3 suppress global translation efficiency in replicatively aged yeast while their activation extends lifespan.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput GSE104507