Details
| Name | GCN4 |
| Type | gene |
| Species | Yeast |
| Tissue | NA |
| Experiment Method | RNA-Seq |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | Moreover, overexpression of Gcn4 sufficed to extend lifespan in an autophagy-dependent manner in the absence of changes in global translation, indicating that Gcn4-mediated autophagy induction is the ultimate downstream target of activated Gcn2, to extend |
| Regulation Gene | NA |
| Year | 2018 |
| Pubmed ID | 30117416 |
| Title | Ssd1 and Gcn4 suppress global translation efficiency in replicatively aged yeast while their activation extends lifespan. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | GSE104508 |