A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name CA1
Type gene
Species Rat
Tissue rat brain
Experiment Method NA
Up/Down NA
Pro/Anti NA
Funtion Description The reducing reagent glutathione rapidly and reversibly depolarized the resting membrane potential of CA1 neurons; the magnitude is time-of-day-dependent and, again, opposite from the SCN. These findings extend circadian redox regulation of neuronal excitability from the SCN to the hippocampus.
Regulation Gene CA1
Year 2020
Pubmed ID 30614107
Title Circadian rhythm of redox state regulates membrane excitability in hippocampal CA1 neurons.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput null