A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name GDF15
Type gene
Species Homo sapiens
Tissue NA
Experiment Method Gene expression analysis
Up/Down up
Pro/Anti pro
Funtion Description Out of analyzed senescence and ER stress markers, the only gene, whose expression correlated negatively with the expression of lipogenic enzymes in both SAT and adipocytes, was GDF15, a marker of not only senescence but also mitochondrial dysfunction. In
Regulation Gene NA
Year 2018
Pubmed ID 30912009
Title Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to GDF15 expression
Drug NA
Disease SAT
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA