A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name GH
Type gene
Species Mus musculus
Tissue blood samples
Experiment Method Western Blotting
Up/Down Up
Pro/Anti Pro
Funtion Description As a consequence of excess GH in their serum, GH transgenic mice exhibited drastically reduced life span which was primarily due to severe kidney lesions (glomerular hypertrophy, sclerosis and hyalinosis associated with tubulo-interstitial changes) consis
Regulation Gene NA
Year 1993
Pubmed ID 8350664
Title Effects of long-term elevated serum levels of growth hormone on life expectancy of mice: lessons from transgenic animal models
Drug NA
Disease NA
Environment Factors NA
Circulating 1
Variant NA
High-throughput NA