A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name NMRK2
Type gene
Species Mouse
Tissue heart
Experiment Method NA
Up/Down UP
Pro/Anti Anti
Funtion Description We investigated the cardiac phenotype of Nmrk2-KO mice to establish its role in cardiac remodeling and function. Young Nmrk2-KO mice developed an eccentric type of cardiac hypertrophy in response to pressure overload rather than the concentric hypertrophy observed in controls.
Regulation Gene NA
Year 2021
Pubmed ID 33805532
Title NMRK2 Gene Is Upregulated in Dilated Cardiomyopathy and Required for Cardiac Function and NAD Levels during Aging
Drug NA
Disease Dilated cardiomyopathy (DCM)
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA