Details
| Name | Beclin1 |
| Type | gene |
| Species | Mouse |
| Tissue | MDCK cells |
| Experiment Method | telomeric repeat amplification protocol method |
| Up/Down | UP |
| Pro/Anti | NA |
| Funtion Description | The recombinant Beclin1-pcDNA3.1 was transfected into MDCK cells. Next, the autophagy information was detected by LC3II staining as autophagy marker using flow cytometry. The telomerase activity was measured by telomeric repeat amplification protocol method in MDCK cells. To detection of the cell death in MDCK cells, apoptosis assay was done through Annexin V staining method. |
| Regulation Gene | NA |
| Year | 2021 |
| Pubmed ID | 33723159 |
| Title | Overexpression of Beclin1 gene leads to reduction of telomerase activity in MDCK cells and enhances apoptosis |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |