A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name ITPR1
Type gene
Species Homo sapiens, Mouse
Tissue human endometrial stromal cells (HESCs)
Experiment Method (RNA) sequencing
Up/Down Down
Pro/Anti Anti
Funtion Description Samples of OE lesions and normal endometrium were obtained. The ITPR1-knockdowned ectopic human endometrial stromal cells (HESCs) were subjected to ribonucleic acid (RNA) sequencing, cell-counting kit-8 (CCK-8) assay, 5-ethynyl-2-deoxyuridine (EdU) staining, and flow cytometry. Camptothecin was administered to HESCs and in an OE mouse model.
Regulation Gene NA
Year 2021
Pubmed ID 33714537
Title Target identification and drug discovery by data-driven hypothesis and experimental validation in ovarian endometriosis
Drug NA
Disease ovarian endometriosis
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA