| Name |
LMNA
|
| Type |
gene
|
| Species |
Homo sapiens
|
| Tissue |
progerin transcripts in patient fibroblasts
|
| Experiment Method |
NA
|
| Up/Down |
NA
|
| Pro/Anti |
NA
|
| Funtion Description |
Of several candidates, PPMO SRP-2001 provided the most significant decrease in progerin transcripts in patient fibroblasts.
|
| Regulation Gene |
NA
|
| Year |
2021
|
| Pubmed ID |
33707773
|
| Title |
A targeted antisense therapeutic approach for Hutchinson-Gilford progeria syndrome
|
| Drug |
NA
|
| Disease |
Hutchinson-Gilford progeria syndrome (HGPS)
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|