A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name P2RX7
Type gene
Species Homo sapiens
Tissue blood
Experiment Method RT-PCR
Up/Down Down
Pro/Anti Anti
Funtion Description we isolated RNA from cultured macrophages at Baseline and evaluated the expression levels of 84 inflammasome-related genes using a custom RT-PCR array. Baseline unstimulated gene expression was associated with age in a single gene (P2RX7) which had a significantly lower expression in older subjects.
Regulation Gene NA
Year 2021
Pubmed ID 35822051
Title Inflammasome Activity in Response to Influenza Vaccination Is Maintained in Monocyte-Derived Peripheral Blood Macrophages in Older Adults.
Drug NA
Disease influenza
Environment Factors NA
Circulating blood
Variant NA
High-throughput NA