| Name |
Hif-p4h-2
|
| Type |
miRNA
|
| Species |
Mouse
|
| Tissue |
blood, gonadal, liver, muscle
|
| Experiment Method |
Real-Time PCR, Western blotting, Glucose tolerance test
|
| Up/Down |
NA
|
| Pro/Anti |
Pro
|
| Funtion Description |
we demonstrate HIF-P4H-2 affected all tissues studied; its inhibition lowered body and liver weight and serum cholesterol levels and improved glucose tolerance.
|
| Regulation Gene |
Slc2a1;Pfk1, Ldha, Pdk1, Pdk4, Irs2, Srebp1c, Acaca, Scd1, Hif-p4h-3
|
| Year |
2022
|
| Pubmed ID |
35787374
|
| Title |
Contribution of HIF-P4H isoenzyme inhibition to metabolism indicates major beneficial effects being conveyed by HIF-P4H-3 antagonism.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
null
|