A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name mAchR1
Type miRNA
Species Mice
Tissue brain
Experiment Method qRT-PCR
Up/Down Up
Pro/Anti Pro
Funtion Description However, young and adult trisomic mice (where cholinergic neurons were present and over-activated) displayed less mAchR1 expression as compared to old trisomic animals (where cholinergic neuron number diminished).
Regulation Gene NA
Year 2022
Pubmed ID 35767135
Title Cholinergic Senescence in the Ts65Dn Mouse Model for Down Syndrome.
Drug NA
Disease Down syndrome
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA