A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Nrf2
Type miRNA
Species Mouse
Tissue liver
Experiment Method NA
Up/Down Up
Pro/Anti Pro
Funtion Description Further analysis revealed that malondialdehyde (MDA) and protein carbonyl (PCO) levels were increased, while nuclear Nrf2 and downstream genes were significantly increased, indicating that oxidative stress induced Nrf2 activation in aged mouse liver.
Regulation Gene NA
Year 2022
Pubmed ID 35699728
Title Nicotinamide Mononucleotide Administration Restores Redox Homeostasis via the Sirt3-Nrf2 Axis and Protects Aged Mice from Oxidative Stress-Induced Liver Injury.
Drug nicotinamide mononucleotide
Disease Oxidative Stress-Induced Liver Injury
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA