A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Dock4
Type miRNA
Species Mice
Tissue brain
Experiment Method knockout genes
Up/Down NA
Pro/Anti Anti
Funtion Description Notably, Dock4 KO mice displayed an age-related decline of hippocampal dependent spatial memory, showing decreased spatial memory in Barnes maze than their WT littermates at late middle age.
Regulation Gene NA
Year 2022
Pubmed ID 35635601
Title Deficiency of Autism-Related Gene Dock4 Leads to Impaired Spatial Memory and Hippocampal Function in Mice at Late Middle Age.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA