A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name MAP4K4
Type piRNA
Species Homo sapiens
Tissue blood
Experiment Method RT-qPCR
Up/Down Up
Pro/Anti Pro
Funtion Description In addition, to verify the reliability of the five hubs ARDEGs, we collected blood samples from AD and healthy individuals to perform quantitative real-time reverse transcription-polymerase chain reaction. The results showed that compared with HCs, the mRNA expression levels of PDGFRB, PLOD1, MAP4K4, and NFKBIA were significantly elevated in AD patients, suggesting they may have the potential to be diagnostic biomarkers for AD.
Regulation Gene NA
Year 2022
Pubmed ID 35615282
Title Identification and Validation of Aging-Related Genes in Alzheimers Disease.
Drug NA
Disease Alzheimers disease
Environment Factors NA
Circulating blood
Variant NA
High-throughput NA