Details
| Name | Elovl2 |
| Type | piRNA |
| Species | Homo sapiens, Mouse |
| Tissue | human fibroblast cell;brain and liver |
| Experiment Method | MeDip-qPCR;qPCR |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | By using a human fibroblast cell model, a dramatic increase of DNA methylation on Elovl2 accompanied with downregulated Elovl2 expression level was detected in aged human fibroblasts. qPCR analysis showed that the expression level of Elovl2 decreased with aging in 129/sv mice. |
| Regulation Gene | NA |
| Year | 2022 |
| Pubmed ID | 35610223 |
| Title | Lipid metabolism dysfunction induced by age-dependent DNA methylation accelerates aging. |
| Drug | NA |
| Disease | NA |
| Environment Factors | DNA damage |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |