A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Sirt1
Type snoRNA
Species Mice
Tissue uterine
Experiment Method NA
Up/Down NA
Pro/Anti Anti
Funtion Description Female mice with uterine ablation of Sirt1 gene using progesterone receptor Cre (PgrCre) exhibit subfertility and signs of premature uterine aging.
Regulation Gene null
Year 2022
Pubmed ID 35536234
Title Uterine-specific SIRT1 deficiency confers premature uterine aging and impairs invasion and spacing of blastocyst, and stromal cell decidualization, in mice.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA