| Name |
GRB2
|
| Type |
gene
|
| Species |
Mus musculus
|
| Tissue |
Eight-week-old and two-year-old male C57BL/6 mice
|
| Experiment Method |
UPLC/Q-TOF MS;Western Blot
|
| Up/Down |
Down
|
| Pro/Anti |
Pro
|
| Funtion Description |
Treatment with fucoidan and fucoxanthin reduced the expression levels of SOS1 and GRB2 while increasing GSK3B, CREB and IRS1 proteins expression in the aging process. Three main metabolic pathways, namely the TCA cycle, glycolysis, and steroid hormone bio
|
| Regulation Gene |
NA
|
| Year |
2019
|
| Pubmed ID |
30669571
|
| Title |
FucoidanFucoxanthin Ameliorated Cardiac Function via IRS1/GRB2/ SOS1, GSK3B/CREB Pathways and Metabolic Pathways in Senescent Mice.
|
| Drug |
fucoidan,fucoxanthin
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|