A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name GRN
Type gene
Species Caenorhabditis elegans
Tissue NA
Experiment Method PCR,other
Up/Down Up
Pro/Anti Anti
Funtion Description Granulin is a protein that in humans is encoded by the GRN gene.Each granulin protein is cleaved from the precursor progranulin, a 593 amino acid long and 68.5 kDa protein. While the function of progranulin and granulin have yet to be determined, both for
Regulation Gene NA
Year 2018
Pubmed ID 29423859
Title Methods to Investigate the Molecular Basis of Progranulin Action on Neurons In Vivo Using Caenorhabditis elegans.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA