A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Gro-1
Type gene
Species Homo sapiens
Tissue Ovarian
Experiment Method SA-B-Gal,Immunohistochemical Staining,Western Blotting
Up/Down Up
Pro/Anti pro
Funtion Description Indeed, Gro-1 seems to be a key molecular link among RAS-mediated transformation, inhibition of apoptosis, senescence of stromal fibroblasts, and tumor progression. Thus, Gro-1 may be the long-sought molecular signal that is activated by oncogenes and oth
Regulation Gene NA
Year 2006
Pubmed ID 17060621
Title The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis
Drug NA
Disease Epithelial Ovarian Cancer
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA