A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name hEST2
Type gene
Species Homo sapiens
Tissue primary normal and tumor tissues
Experiment Method qPCR
Up/Down Up
Pro/Anti Anti
Funtion Description hEST2 is expressed at high levels in primary tumors, cancer cell lines, and telomerase-positive tissues but is undetectable in telomerase-negative cell lines and differentiated telomerase-negative tissues. Moreover, the message is up-regulated concomitant
Regulation Gene NA
Year 1997
Pubmed ID 9288757
Title hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization.
Drug NA
Disease lymphoma;leukemia
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA