Details
| Name | ASF/SF2 |
| Type | alternative splicing |
| Species | Homo sapiens |
| Tissue | Human embryonic kidney 293T cells |
| Experiment Method | Western Blotting,qPCR |
| Up/Down | NA |
| Pro/Anti | NA |
| Funtion Description | In this work, we demonstrate that the alternative splicing factor or splicing factor-2 (ASF/SF2) is involved in the synthesis of endoglin. Overexpression of ASF/SF2 in endothelial cells switched the balance between the two endoglin isoforms, favoring the |
| Regulation Gene | endoglin |
| Year | 2011 |
| Pubmed ID | 21668763 |
| Title | Alternative splicing factor or splicing factor-2 plays a key role in intron retention of the endoglin gene during endothelial senescence |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |