A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name hMT-3
Type gene
Species Homo sapiens
Tissue brain
Experiment Method Western blot, qRT-PCR, Electrochemical microarray
Up/Down Up
Pro/Anti Pro
Funtion Description Overall, our data strongly suggest that up-regulation of hMT-3 positively correlates with the genes involved in oncogene-induced senescence (CDKN2B and ANAPC5) or apoptosis (CASP4). Moreover, we identified a significant increase in chemoresistance to cisp
Regulation Gene NA
Year 2018
Pubmed ID 29435113
Title Comparative gene expression profiling of human metallothionein-3 up-regulation in neuroblastoma cells and its impact on susceptibility to cisplatin
Drug cisplatin
Disease neuroblastoma
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA