A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name HO-1
Type gene
Species Rat Rattus
Tissue The knee joint cartilages of five-week-old female Sprague-Dawley rats
Experiment Method SABgal staining;Western blot
Up/Down Up
Pro/Anti Anti
Funtion Description The association between HO1 and cellular senescence was also examined in CK2 inhibitortreated chondrocytes. Pretreatment with 3morpholinosydnonimine hydrochloride, an inducer of the HO1 expression, or overexpression of the HO1 gene significantly delayed c
Regulation Gene NA
Year 2019
Pubmed ID 30535443
Title Inhibition of protein kinase CK2 facilitates cellular senescence by inhibiting the expression of HO-1 in articular chondrocytes.
Drug TBB,DRB
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA