A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name WRN
Type CNV
Species Homo sapiens
Tissue NA
Experiment Method CHIP,PCR
Up/Down NA
Pro/Anti Pro
Funtion Description Loss-of-function mutations in WRN lead to genomic instability, an elevated cancer risk, and premature cellular senescence.
Regulation Gene WRN
Year 2003
Pubmed ID 12842909
Title Werner syndrome protein limits MYC-induced cellular senescence.
Drug NA
Disease WRN syndrome
Environment Factors NA
Circulating NA
Variant CNV
High-throughput NA