| Name |
HSP27
|
| Type |
gene
|
| Species |
Homo sapiens
|
| Tissue |
MRC-5 human lung fibroblast cells
|
| Experiment Method |
Immunoblot;siRNA transfection;Quantitative PCR;Immunocytochemistry
|
| Up/Down |
Down
|
| Pro/Anti |
Pro
|
| Funtion Description |
Moreover, we observed cellular senescence in MRC-5 cells on day 3 after the HSP27 knockdown, as evidenced by increased senescence-associated B-gal activity and up-regulated inflammatory cytokines. The cellular senescence was also suppressed by the concomi
|
| Regulation Gene |
NA
|
| Year |
2018
|
| Pubmed ID |
30166342
|
| Title |
Heat shock protein 27 promotes cell cycle progression by down-regulating E2F transcription factor 4 and retinoblastoma family protein p130.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|