A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name hTRT
Type gene
Species Homo sapiens
Tissue Normal human diploid cell
Experiment Method qPCR
Up/Down Up
Pro/Anti Anti
Funtion Description In contrast to telomerase-negative control clones, which exhibited telomere shortening and senescence, telomerase-expressing clones had elongated telomeres, divided vigorously, and showed reduced straining for beta-galactosidase, a biomarker for senescenc
Regulation Gene NA
Year 1998
Pubmed ID 9454332
Title Extension of life-span by introduction of telomerase into normal human cells.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA