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Details


Name EZH2
Type enhancer
Species Homo sapiens
Tissue cells SGC-7901
Experiment Method NA
Up/Down Up
Pro/Anti Anti
Funtion Description We found that EZH2 functionally suppressed the senescent state in human gastric cancer cells SGC-7901. EZH2 depletion inhibited cell proliferation, arrested cellular cycle, restored features of a cellular senescence phenotype, and promoted doxorubicin-ind
Regulation Gene zeste homolog 2
Year 2014
Pubmed ID 24588771
Title Inhibiting enhancer of zeste homolog 2 promotes cellular senescence in gastric cancer cells SGC-7901 by activation of p21 and p16.
Drug NA
Disease gastric cancer
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA