| Name |
IGF1
|
| Type |
gene
|
| Species |
Homo sapiens
|
| Tissue |
Skin biopsies of patients,mouse embryos
|
| Experiment Method |
other
|
| Up/Down |
NA
|
| Pro/Anti |
NA
|
| Funtion Description |
Unrepaired cytotoxic DNA damage induces a highly conserved metabolic response mediated by the IGF1/insulin pathway, which re-allocates resources from growth to somatic preservation and life extension.
|
| Regulation Gene |
NA
|
| Year |
2006
|
| Pubmed ID |
17183314
|
| Title |
A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|