A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name IGF1
Type gene
Species Mus musculus
Tissue brain and liver tissues
Experiment Method Western Blot Analysis;Quantitative Real-Time PCR
Up/Down Down
Pro/Anti Pro
Funtion Description Insulin-like growth factor (IGF)-1 plays an important role in the regulation of cellular and tissue functions, and relating to the aging process the most important pathway of IGF-1 is the phosphatidylinositol 3-kinase (PI3K) and protein kinase B (Akt/PKB)
Regulation Gene NA
Year 2017
Pubmed ID 27718093
Title Differential Regulation of Hippocampal IGF-1-Associated Signaling Proteins by Dietary Restriction in Aging Mouse.
Drug NA
Disease NA
Environment Factors DR
Circulating NA
Variant NA
High-throughput NA