Details
| Name | IGF1 |
| Type | gene |
| Species | Homo sapiens |
| Tissue | Breast |
| Experiment Method | Real-time reverse transcription-PCR,Western blot,other |
| Up/Down | NA |
| Pro/Anti | NA |
| Funtion Description | Klotho is an anti-aging gene, which has been shown to inhibit the insulin and insulin-like growth factor 1 (IGF-1) pathways in mice hepatocytes and myocytes. As IGF-1 and insulin regulate proliferation, survival and metastasis of breast cancer, we studied |
| Regulation Gene | NA |
| Year | 2008 |
| Pubmed ID | 18762812 |
| Title | Klotho: a tumor suppressor and a modulator of the IGF-1 and FGF pathways in human breast cancer. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |