A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name IGF1
Type gene
Species Mus musculus
Tissue WI38,U118MG,LN229,U87MG,C6,IGFIR-
Experiment Method other
Up/Down Down
Pro/Anti NA
Funtion Description The insulin-like growth factor type 1 (IGF-I) plays an important role in neuronal physiology. Reduced IGF-I levels are observed during aging and this decrease may be important to age-related changes in the brain. We studied the effects of IGF-I on total p
Regulation Gene NA
Year 2009
Pubmed ID 19896963
Title Activation of proteasome by insulin-like growth factor-I may enhance clearance of oxidized proteins in the brain.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA