Details
| Name | IGF1 |
| Type | gene |
| Species | Mus musculus |
| Tissue | liver |
| Experiment Method | RT-PCR,DNA microarray |
| Up/Down | Down |
| Pro/Anti | Pro |
| Funtion Description | Serum IGF-I was reduced by approximately 80% in mice with adult, liver-specific IGF-I inactivation (LI-IGF-I(-/-) mice), and body weight decreased due to reduced body fat. The mean life span of LI-IGF-I(-/-) mice (n=84) increased 10% vs. control mice (n=1 |
| Regulation Gene | NA |
| Year | 2011 |
| Pubmed ID | 21799924 |
| Title | Liver-derived IGF-I regulates mean life span in mice. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |