A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name IGF1
Type gene
Species Mus musculus
Tissue NA
Experiment Method RT-PCR
Up/Down Up
Pro/Anti NA
Funtion Description increase in hippocampal GH and IGF-1 protein expression and subsequent activation of PI3K/Akt-CREB signal transduction cascade might contribute to the maintenance of cognitive function and is likely to be responsible for the integrity of neuronal structur
Regulation Gene NA
Year 2005
Pubmed ID 15718052
Title Local expression of GH and IGF-1 in the hippocampus of GH-deficient long-lived mice.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA