A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name IGF1R
Type gene
Species Rat Rattus
Tissue vascular smooth muscle cell (VSMC)
Experiment Method Western blot,other
Up/Down Up
Pro/Anti Pro
Funtion Description Insulin-like growth factor-1 receptor (IGF-1R) promotes aortic vascular smooth muscle cell (VSMC) growth, migration, and extracellular matrix formation.we compared IGF-1R expression in early passages of VSMC and found a constitutive activation of IGF-1R i
Regulation Gene NA
Year 2008
Pubmed ID 18615585
Title Age-related differences in insulin-like growth factor-1 receptor signaling regulates Akt/FOXO3a and ERK/Fos pathways in vascular smooth muscle cells.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA