| Name |
IGF1R
|
| Type |
gene
|
| Species |
Mus musculus
|
| Tissue |
Brain
|
| Experiment Method |
RT-PCR,Western blot,other
|
| Up/Down |
Down
|
| Pro/Anti |
Pro
|
| Funtion Description |
Mutations that decrease insulin-like growth factor (IGF) and growth hormone signaling limit body size and prolong lifespan in mice. In vertebrates, these somatotropic hormones are controlled by the neuroendocrine brain. Hormone-like regulations discovered
|
| Regulation Gene |
NA
|
| Year |
2008
|
| Pubmed ID |
18959478
|
| Title |
Brain IGF-1 receptors control mammalian growth and lifespan through a neuroendocrine mechanism.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|