| Name |
p16
|
| Type |
enhancer
|
| Species |
Homo sapiens
|
| Tissue |
The androgen-dependent growing human prostate cancer cell line, LNCaP (lymph node prostate cancer);Human prostate tissue samples
|
| Experiment Method |
qRT-PCR;Protein immunodetection;ChIP;
|
| Up/Down |
NA
|
| Pro/Anti |
Pro
|
| Funtion Description |
AA treatment of living cells provokes molecular changes of AR signaling. In addition to a deceleration of nuclear translocation a block of the intramolecular amino/carboxy (N/C)-terminal interaction of the AR was observed. Using inhibitors of the non-rece
|
| Regulation Gene |
NA
|
| Year |
2014
|
| Pubmed ID |
25203674
|
| Title |
A natural androgen receptor antagonist induces cellular senescence in prostate cancer cells.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|