| Name |
IGFBP-rP1
|
| Type |
gene
|
| Species |
Homo sapiens
|
| Tissue |
endometrial cell line
|
| Experiment Method |
western blot;PCR;Flow cytometry;SA-B-Gal staining
|
| Up/Down |
NA
|
| Pro/Anti |
Pro
|
| Funtion Description |
It was observed that IGFBPrP1 transfection inhibited cell growth, and induced G1 phase arrest and cellular senescence in HEC1A cells while gene silencing presented the adverse functional changes.
|
| Regulation Gene |
NA
|
| Year |
2017
|
| Pubmed ID |
29067463
|
| Title |
IGFBP-rP1 acts as a potential tumor suppressor via the suppression of ERK signaling pathway in endometrial cancer cells.
|
| Drug |
NA
|
| Disease |
endometrial cancer
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|