Details
| Name | IGF-I |
| Type | gene |
| Species | Mus musculus |
| Tissue | liver tissues |
| Experiment Method | Western Blotting |
| Up/Down | Down |
| Pro/Anti | Pro |
| Funtion Description | The results of this study demonstrate that GH(growth hormone) induces phosphorylation of JAK2 and the GHR complex, activates MAP kinase, and increases the expression of IGF-I messenger RNA in liver. In 17-month-old animals, decreases in IGF-I gene express |
| Regulation Gene | NA |
| Year | 1995 |
| Pubmed ID | 7664676 |
| Title | Decreases in growth hormone receptor signal transduction contribute to the decline in insulin-like growth factor I gene expression with age. |
| Drug | NA |
| Disease | NA |
| Environment Factors | growth hormone |
| Circulating | 1 |
| Variant | NA |
| High-throughput | NA |