A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name IGF-I
Type gene
Species Mus musculus
Tissue extensor digitorum longus muscles
Experiment Method qPCR
Up/Down Up
Pro/Anti Anti
Funtion Description We demonstrate that the IGF-I expression promotes an average increase of 15% in muscle mass and a 14% increase in strength in young adult mice, and remarkably, prevents aging-related muscle changes in old adult mice, resulting in a 27% increase in strengt
Regulation Gene NA
Year 1998
Pubmed ID 9861016
Title Viral mediated expression of insulin-like growth factor I blocks the aging-related loss of skeletal muscle function
Drug NA
Disease NA
Environment Factors NA
Circulating 1
Variant NA
High-throughput NA