A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name IGF-I
Type gene
Species Mus musculus
Tissue blood samples
Experiment Method qPCR
Up/Down Down
Pro/Anti Pro
Funtion Description We chose to study the effects of loss of GH signaling on growth and aging in a mouse model for Laron Syndrome (LS) in which the GHR/BP gene has been disrupted. We observed that mice homozygous for the disruption (-/-) were significantly smaller than norma
Regulation Gene NA
Year 2000
Pubmed ID 10875265
Title Assessment of growth parameters and life span of GHR/BP gene-disrupted mice.
Drug NA
Disease NA
Environment Factors NA
Circulating 1
Variant NA
High-throughput NA