A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name IGF-I
Type gene
Species Homo sapiens
Tissue blood samples
Experiment Method immunoradiometric assay
Up/Down Down
Pro/Anti Pro
Funtion Description The elderly subjects had plasma IGF-I levels and integrated GH concentrations that were 32% to -56% of their sex-matched younger counterparts. The age-associated attenuation in GH was due to a decrease in GH pulse amplitude, whereas pulse frequency and na
Regulation Gene NA
Year 2001
Pubmed ID 11213276
Title Aging-related growth hormone (GH) decrease is a selective hypothalamic GH-releasing hormone pulse amplitude mediated phenomenon.
Drug NA
Disease NA
Environment Factors NA
Circulating 1
Variant NA
High-throughput NA