Details
| Name | Il-1B |
| Type | gene |
| Species | Mus musculus |
| Tissue | senescence-accelerated mouse-prone 8 (SAMP8) mice |
| Experiment Method | Western Blotting; Reverse transcription-polymerase chain reaction (RT-PCR);Real-time quantitative PCR (qPCR) |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | gene expression of oxidative stress (OS) and inflammatory markers, such as Hmox1, Aldh2, Il-1B, and Ccl3, were reduced in old treated mice in comparison to that of the control group. Consistent with this, we further demonstrate a significant correlation w |
| Regulation Gene | NA |
| Year | 2018 |
| Pubmed ID | 29611102 |
| Title | 11B-HSD1 Inhibition by RL-118 Promotes Autophagy and Correlates with Reduced Oxidative Stress and Inflammation, Enhancing Cognitive Performance in SAMP8 Mouse Model |
| Drug | RL-118 |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |