A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name IL-6
Type gene
Species Rat Rattus
Tissue adipose tissue
Experiment Method qPCR
Up/Down Up
Pro/Anti Pro
Funtion Description Aged rats had significantly higher Il6, MuRF1, and Atrogin1 but not Il1b and Tnfa, expression and greater levels of IMAT in their quadricep muscles than young rats. Our results suggest that elevated leptin levels due to aging cause ectopic inflammation th
Regulation Gene NA
Year 2019
Pubmed ID 31077169
Title Elevated leptin levels induce inflammation through IL-6 in skeletal muscle of aged female rats
Drug NA
Disease intervertebral disc degeneration
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA