| Name |
p21
|
| Type |
enhancer
|
| Species |
Mus musculus
|
| Tissue |
Human ES cell line (H9) with a stable normal (46XX) karyotype
|
| Experiment Method |
Western blotting;Real-time quantitative PCR; Immunocytochemistry
|
| Up/Down |
Up
|
| Pro/Anti |
Pro
|
| Funtion Description |
MPTP-treated NPCs were found to undergo premature senescence determined by increased senescence-associated-B-galactosidase (SA-B-gal) activity, elevated intracellular reactive oxygen species level, and decreased proliferation] and were associated with imp
|
| Regulation Gene |
NA
|
| Year |
2015
|
| Pubmed ID |
26159917
|
| Title |
Rejuvenation of MPTP-induced human neural precursor cell senescence by activating autophagy.
|
| Drug |
1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP),rapamycin
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|