| Name |
iNOS
|
| Type |
gene
|
| Species |
Mus musculus
|
| Tissue |
bone marrow-derived macrophages (BMDMs)
|
| Experiment Method |
Polymerase chain reaction(PCR) ; enzyme-linked immunosorbent assay (ELISA);quantitative polymerase chain reaction (qPCR);
|
| Up/Down |
Down
|
| Pro/Anti |
Pro
|
| Funtion Description |
The higher susceptibility of elderly mice to T. cruzi infection was accompanied by reduced cardiac inducible nitric oxide synthase (iNOS) gene expression, nitric oxide (NO) and IFN-r levels, as well as an antagonistic upregulation of arginase-1 expression
|
| Regulation Gene |
NA
|
| Year |
2018
|
| Pubmed ID |
30248443
|
| Title |
Impact of Trypanosoma cruzi infection on nitric oxide synthase and arginase expression and activity in young and elderly mice
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|