A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name INS
Type gene
Species Mus musculus
Tissue NA
Experiment Method PCR,other
Up/Down NA
Pro/Anti Anti
Funtion Description Recent evidence suggests that alterations in insulin/insulin-like growth factor 1 (IGF1) signaling (IIS) can increase mammalian life span. For example, in several mouse mutants, impairment of the growth hormone (GH)/IGF1 axis increases life span and also
Regulation Gene NA
Year 2008
Pubmed ID 17928362
Title Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA